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New Year, Less Noise: A Practical Biohacking Reset
A 30‐day, data‐driven reset to cut the noise, stabilize your foundations, and make every biohack you keep actually count.
Jeffrey Nunn
January 07, 2026
Happy New Year Biohackers,
I’ve thought about this issue for a few weeks and what the new year brings to upgrading my body. I hope everyone took advantage of the holiday and new year sale to pick up supplements and peptides at a discount as I did. I hit Sprouts for 30% off vitamins and supplements and then loaded up on bioregulators from Biolongevity Labs for a healthy 55% off. I plan to focus on my workouts, nutrition and sleep. And yes peptides.
Followers of this newlsetter with rock 2026 like its the best year in history and health, thats you. Lets go!!!
Affiliate Disclosure: This newsletter contains affiliate links. When you purchase through these links using code PROBIO15, I may earn a commission at no additional cost to you. I only recommend vendors I personally use and trust.
Table of Contents
2026 Reset
If 2025 left you with too many supplements, half‑finished protocols, and a stack of data you never look at, this issue is about stripping things back to what works, then layering the fun stuff on top with intention instead of guesswork.
Giphy
The 3‑Layer Biohacking Stack
Most people jump straight into red light, exotic peptides, and nootropics while their basics are on fire. Use this 3‑layer stack to reset how you think about your protocols.
Layer 1 – Foundations: Sleep timing, morning light, daily movement, protein, and blood sugar control are the baseline that determines whether anything advanced actually works.
Layer 2 – Signals: HRV, sleep staging from wearables, simple labs, and subjective tracking (energy, mood, focus) tell you if your “hacks” are doing anything.
Layer 3 – Levers: Peptides, nootropics, sauna, cold, and devices are the multipliers that you earn once Foundations are at least 7/10 and you are tracking at least one signal.
A simple rule for this month: no new “lever” unless your Foundations are stable and you have one way to measure change.
30‑Day Biohacking Reset
Think of the next 30 days as a de‑clutter for your physiology. Use this as a simple framework you can actually follow with a normal schedule.
Week 1 – Baseline & Cleanup
Track: sleep (duration + consistency), HRV if you have a wearable, and a 1–10 rating for energy, mood, and focus each day.
Remove: 1–2 non‑essential supplements or stacks so you can actually see what’s doing what.
Add: one non‑negotiable—consistent wake time plus 5–15 minutes of morning light within 60 minutes of waking.
Week 2 – Metabolic & Stress
Dial in: a protein target per meal, an evening food cut‑off (2–3 hours before bed), and a 5–10 minute walk after your biggest meal.
Add: one down‑regulation anchor for the nervous system at least 5 days this week (breathwork, yoga nidra, or a guided relaxation).
Review: note any shifts in mood, cravings, and ability to focus by comparing to last week’s 1–10 ratings.
Week 3–4 – Targeted Levers
Choose ONE main goal: sleep, body composition, focus, or recovery.
Pick 1–2 advanced levers that map directly to that goal (for example: sleep‑focused peptide protocol, a specific nootropic stack, or a light/temperature routine).
Track: one objective metric (HRV, deep sleep minutes, bodyweight, or training performance) plus one subjective rating (how you feel) before and after the 2‑week block.
Inside My Own Experiment Log
To keep this practical, here is how this reset looks in a real‑world experiment.
Goal: increase deep sleep by 20% over four weeks without wrecking daytime performance.
Levers: tightening caffeine cut‑off to before noon, consistent wake time, evening light hygiene, and a targeted sleep‑support peptide stack layered in after Week 1.
Data: deep and REM sleep from a wearable, a daily 1–10 score for morning alertness, and a simple note on training recovery.
The main lesson: the biggest jump came from boring changes—caffeine timing and light—before the advanced stack ever had room to show up in the data.
What I’m Paying Attention To in 2026
Cutting noise also means being selective about trends. Here are a few currents that are actually interesting for serious biohackers right now.
Peptides and longevity: increasing interest in longevity‑oriented peptides and combination protocols demands better tracking and more conservative, data‑driven experimentation.
Data‑centric biohacking: the shift toward using HRV, wearables, and short, well‑designed experiments instead of endless stack‑building is accelerating.
Overhyped tech: some high‑ticket devices and extreme protocols continue to outpace the quality of human data behind them, which makes a “foundations first” approach even more valuable.
How to Put This Into Action
If this resonated, do not add anything new yet—start by deleting. Pick your 30‑day reset window, choose one main goal, and let this framework guide what stays and what goes in your stack.
If you want help designing a data‑driven protocol around your specific goals, reply to this email with the word RESET and a sentence about your main target for the next 90 days.
New Year, Less Noise: A Practical Biohacking ResetPeptide Industry News
There is a huge crackdown on GLP’s. If you can find them they will most likely be under a different name. As I find them I will let you know in this newsletter.
Peptide Protocols
DSIP (Delta Sleep-Inducing Peptide) – Protocol Overview
DSIP is an endogenous neuropeptide associated with regulation of deep (slow-wave) sleep and nighttime autonomic balance. Unlike sedatives, it does not force sleep; instead, it helps normalize sleep architecture, reduce nighttime cortisol, and calm sympathetic nervous system activity.
Primary benefits include improved sleep onset, fewer nighttime awakenings, deeper restorative sleep, and reduced nocturnal heart rate or blood pressure fluctuations. DSIP is especially useful for stress-related insomnia, post-menopausal sleep disruption, and individuals who do not tolerate melatonin or GABA-based sleep aids.
Dose:
Inject 200 mcg subcutaneously (SC).
Timing:
Administer 30–60 minutes before bedtime, ideally on an empty stomach or at least 2–3 hours after food.
Frequency & Cycling:
Use nightly for 5–10 consecutive nights, then take 7–14 days off. DSIP works best in short cycles rather than continuous use.
Expected effects:
Most users notice calmer evenings within the first few nights, followed by deeper sleep and improved sleep continuity by nights 4–7. Improvements often persist after the cycle ends.
Safety:
DSIP is non-sedating, non-habit forming, and typically does not cause morning grogginess. Vivid dreams or mild stimulation usually indicate excessive dosing.
Project Biohacking Resources
Quick note on affiliates: The vendor links and discount codes in this newsletter are affiliate partnerships. This means when you use code PROBIO15, I receive a small commission—but your price stays the same (or gets better with the discount). I only partner with peptide sources I've personally vetted and used. Your purchases help keep Project Biohacking running and allow me to continue creating free educational content.
Quick links to Peptide Sources listed Discount Codes
👇🏻Peptides👇🏻
Biolongevity Labs - PROBIO15 for 15% off
Limitless Biotech - PROBIO15 for 15% off
Rejuvatide Peptides - PROBIO15 for 15% off
CanLabs Intl - PROBIO15 for 15% off
👇🏻Oral Bioregulators👇🏻
Vita Stream - Use PROBIO10 for 10% off
👇🏻Supplements👇🏻
👇🏻Labs👇🏻
Guides
From Around The Web
🔚 Outro & Final Thoughts
Your next move isn’t adding more—it’s cutting what doesn’t work. For the next 30 days, run your body like a results-driven experiment and keep only what delivers real gains. Strip it down, lock in the fundamentals, and let outcomes—not trends—decide what stays. If you want a clear, personalized reset plan, hit COACHING RESET with your top goal for the next 90 days and I’ll build your roadmap.
Until next time, stay ahead of your age!
– Jeff
Founder, Project Biohacking
Disclaimer: I’m here to share what I’ve learned, not to replace your doctor. Always check with a qualified healthcare provider before trying anything new. And yes, peptides are often for research use only; please don’t turn your kitchen into a chemistry lab without supervision.