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- Project Biohacking Newsletter – August 11, 2025
Project Biohacking Newsletter – August 11, 2025
Joe Rogan Talks Peptides + How I Healed My Dog’s Injury Naturally
Jeffrey Nunn
August 11, 2025
Peptides aren’t just for elite athletes anymore; they’re showing up everywhere from mainstream podcasts to the vet’s office.
Table of Contents
Introduction
Welcome to this week’s dose of Project Biohacking. We have curated content, real-world case studies, and peptide protocols you can actually use.
This week, we’ve got two big ones for you:
Joe Rogan and Dr. Andrew Huberman engage in a high-profile discussion, introducing peptides into the mainstream discourse.
My personal story of using targeted peptide therapy to heal my dog’s injury when conventional treatments fell short.
Let’s dive in.
Curated Content – Joe Rogan Talks Peptides
BPC-157: The Peptide Joe Rogan and Dr. Andrew Huberman Can't Stop Talking About
When two of the most influential voices in health and performance—Joe Rogan and Andrew Huberman—both rave about the same compound, it's worth paying attention. Enter BPC-157, the healing peptide that's captured their attention and transformed their personal recovery experiences.
What Got Them Hooked
Joe Rogan's Breakthrough: The UFC commentator and podcaster had been battling stubborn elbow tendonitis that just wouldn't quit. Traditional treatments were not effective. Then he tried BPC-157. Within just two weeks, his inflammation and pain had vanished completely. "It was like magic," Rogan described on his podcast, crediting the peptide with solving a problem that had plagued him for months.
Andrew Huberman's Relief: The Stanford neuroscientist was dealing with persistent L5 spinal compression pain—the kind of chronic discomfort that affects everything you do. After just two BPC-157 injections, Huberman experienced complete pain relief from an issue that had troubled him for an extended period. As someone who lives and breathes scientific rigor, his endorsement carries serious weight.
Why These Experiences Matter
Neither Rogan nor Huberman is a paid spokesperson. They're sharing genuine personal results from a compound they discovered, tested, and found transformative. Huberman brings scientific credibility and methodical analysis, while Rogan offers the perspective of someone constantly pushing physical limits through martial arts and intense workouts.
Their combined endorsement represents something powerful: real-world results backed by scientific understanding.
What Is BPC-157?
BPC-157 (Body Protection Compound 157) is a synthetic peptide made of 15 amino acids, derived from proteins naturally found in the human stomach lining. Think of it as your body's repair system amplified—it promotes rapid healing in muscles, tendons, ligaments, and even gut tissue.
The peptide works by:
Accelerating cellular regeneration and tissue repair
Stimulating blood vessel growth for better circulation
Reducing inflammation without harsh pharmaceutical side effects
Supporting your body's natural healing mechanisms
The Rogan-Huberman Protocol
Based on their shared experiences and discussions:
Dosing: 250-500 mcg daily via subcutaneous injection Duration: 2-6 week cycles. Application: Inject near the problem area for targeted healing. Results: Both saw significant improvement within 2 weeks
Huberman emphasizes the importance of proper dosing and cycling, while Rogan advocates for combining it with other recovery modalities like sauna, cold therapy, and proper nutrition.
What You Might Experience
Following their lead, users report:
Dramatically faster injury recovery
Reduced chronic pain and inflammation
Enhanced muscle and tendon repair
Improved joint mobility
Better exercise recovery
Enhanced overall tissue resilience
The Rogan Factor: Performance and Longevity
For Rogan, BPC-157 fits into his broader biohacking philosophy. At 56, he maintains the physical capacity of someone decades younger, and he credits compounds like BPC-157 as part of his longevity strategy. He views it not just as injury treatment but as performance optimization and preventive medicine.
The Huberman Perspective: Science Meets Application
Huberman applies the principles of neuroscience and evidence-based medicine to the study of BPC-157. He appreciates the mechanism of action of BPC-157 and how it aligns with our understanding of tissue repair and inflammation. His methodical approach and scientific background provide credibility to claims that may otherwise appear implausible.
Why Their Endorsement Matters
When two people with such different backgrounds—entertainment/athletics and academic neuroscience—independently discover and endorse the same compound, it suggests something significant. Their combined reach has introduced millions to BPC-157, sparking broader conversations about peptide therapy and recovery optimization.
The Reality Check
Both Rogan and Huberman are clear about important caveats:
BPC-157 isn't FDA-approved for therapeutic use
Most research is animal-based, though human experiences are promising
Individual results vary
Professional guidance is recommended
It's a tool, not a magic bullet
Following Their Lead
If the experiences of Rogan and Huberman inspire you, then approach BPC-157 seriously.
Start with lower doses to assess tolerance
Work with a knowledgeable practitioner
Combine with solid fundamentals (sleep, nutrition, movement)
Cycle on and off to prevent tolerance
Monitor your response carefully
The Bottom Line
Joe Rogan and Andrew Huberman represent different paths to the same discovery: BPC-157 as a game-changing tool for healing and recovery. Their personal success stories, combined with their massive platforms, have brought this peptide into mainstream health conversations.
Whether you're dealing with chronic pain like Huberman, performance demands like Rogan, or simply want to optimize your body's healing capacity, their experiences suggest BPC-157 deserves serious consideration, with proper guidance and realistic expectations.
Announcements
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The dates for next month's meetup will be announced in a few weeks, along with additional details. Sign up now so you don’t miss it!
Join us on in
Affiliate Content (aka: how I keep the lights on and my peptides cold)
Occasionally I recommend products I love, and if you buy through my links, I may earn a small commission. It doesn’t cost you extra, but it does help fund my n=1 experiments… like seeing how many peptides I can fit in one fridge drawer. So, this week it’s Pique Life.👇🏻👇🏻👇🏻👇🏻👇🏻👇🏻👇🏻👇🏻👇🏻👇🏻👇🏻👇🏻👇🏻👇🏻👇🏻👇🏻👇🏻👇🏻👇🏻👇🏻👇🏻👇🏻👇🏻👇🏻👇🏻👇🏻👇🏻👇🏻👇🏻👇🏻👇🏻👇🏻
Hydrated Skin. Deeper Sleep. One Daily Ritual!
I used to feel dry, foggy, and drained—until I tried Pique’s Deep Hydration Protocol. This day-to-night electrolyte duo hydrates skin, calms the nervous system, and supports deep sleep. No sugar, no fillers—just results. I feel clear, radiant, and truly hydrated.
Healing Protocols Spotlight
From Our Latest Truth Health Seekers Circle
In our recent private meetup, the conversation focused on practical, real-world healing protocols that members have used successfully. Below is a distilled, name-free summary you can use to inspire your health journey.
1. Green Coffee Enema Detox
Purpose: Deep liver detoxification, toxin removal, and glutathione stimulation.
How It Works:
Uses unroasted, gold-colored, shade-grown green coffee for a low-retention enema.
Opens bile ducts, releasing toxins directly from the liver for elimination.
It aids the body in producing glutathione, a potent antioxidant.
Additional Benefits:
Provides temporary pain relief (1–1.5 hours).
Bypasses the gut, protecting beneficial bacteria.
Add-Ins (3–4× per week):
Oregano oil (antiparasitic)
Magnesium powder (muscle relaxation & bowel support)
Garlic (antimicrobial & antiparasitic)
Pro Tip: Liquid peptides can be added to the enema solution for needle-free delivery.
2. Glutathione Optimization Without Oral Supplements
Why: Oral glutathione is poorly absorbed. Instead, focus on stimulating your body’s own production.
Protocol:
Support liver function (see Green Coffee Enema above).
Supplement NAC (1000 mg) + Glycine (1000 mg) daily for the necessary building blocks.
Especially valuable for detox after heavy metal exposure or injections.
3. Key Peptide Healing Strategies
BPC-157
Duration: 90-day course.
Benefits: Eliminates chronic pain, repairs tendons, ligaments, and muscle tissue.
Works regardless of injury origin.
Thymosin Alpha-1
Benefits: Immune modulation and autoimmune support.
It is effective for treating chronic viral conditions that have not responded to other protocols.
NAD+
Benefits: Improves energy, circadian rhythm, mitochondrial health, and brain function.
Often paired with other peptides for enhanced recovery and longevity.
4. Mitochondrial Optimization Stack
Current Stack Example:
SS-31 - Repairs mitochondrial structure.
MOTS-c - Stimulates new mitochondria formation (biogenesis).
Quercetin - Protects NAD⁺ levels by suppressing the CD38 enzyme.
Chlorella + Spirulina – Reduces oxidative stress via superoxide dismutase activation.
Emerging Peptides to Watch:
BAM15 – Targets visceral fat.
SLUP-332 – Supports mitochondrial health via estrogen receptor modulation.
5. Key Takeaways from the Circle
Detox is ongoing - liver health is central to any healing program.
Custom protocols win - tailor stacks to your personal health goals.
Synergy matters - peptides work best alongside a clean diet, natural detox, and lifestyle optimization.
Delivery methods can be flexible - injections, oral dosing, topical use, and even enema administration are options depending on comfort level and goals.
When Peptides Saved My Dog's Life
Real Story Alert: From Emergency Surgery to Complete Healing
Yesterday, I shared a blog post about how I healed my dog with peptides. Today, I'm expanding on that post with pictures and additional details.
Warning: The images below show graphic veterinary injuries
11/05/2024 - first vet visit for Zeus
This is what I woke up to find on my dog Zeus. A hematoma had burst, and he'd chewed through his skin down to the bone overnight. "Horrifying" doesn't begin to describe it.
The emergency vet's verdict? The vet recommended a $4,000 surgery and 8-10 weeks of intensive care.
Instead, I tried something unconventional: the same BPC-157 and TB-500 peptides we've discussed for human healing.
11/12/2024 - 1 week into the Wolverine Protocol
Seven days later, even the vet was shocked. "You don't need to come back weekly anymore," she said, staring at the dramatic improvement.
12/06/2024 - 4 weeks and 3 days from injury
One month total. The wound has transformed from a gaping hole to a tiny scab that is barely noticeable.
The numbers that matter:
Traditional treatment: $4,000 + 2-3 months recovery
Peptide protocol: $700 + 1 month complete healing
However, what truly shocked me was the discovery we made months later: Zeus had hip dysplasia. Instead of surgery, I kept him on maintenance peptides every 6 months.
Today? He runs, jumps, and plays like the injury never happened. His hip dysplasia? His hip dysplasia doesn't cause him any discomfort.
Why I'm Sharing This
If peptides can effectively heal a severe wound on a 1.5-year-old dog, just imagine the potential benefits they could have for aging pets, chronic conditions, or post-surgical recovery.
This isn't veterinary advice; it's one owner's real experience with regenerative medicine that most vets don't even know exists yet.
Want the full story? I've documented everything: the timeline, exact protocols, costs, and what I learned about dosing peptides for dogs.
The photos tell the story, but the details might help your own four-legged family member.
From Around The Web
Peptides are one of the most powerful healing tools we have, but the FDA says they’re not needed.
That’s because they’re repeating what pharmaceutical lobbyists told them.
But here’s the truth:
✅ Insulin is a peptide
✅ Peptides are short-chain amino acids naturally found in— Gary Brecka (@thegarybrecka)
1:00 PM • Aug 3, 2025
🔮 Next Issue Preview
In our next issue of Project Biohacking Why Women Lose Their CurvesWe’ll dive into the science of visceral fat. We will explore the hidden fat that surrounds your organs and explain why so many women start to lose their natural curves as they get older. You’ll learn:
Make sure you don’t miss it, it’s one of the most misunderstood topics in women’s health. |
🔚 Outro & Final Thoughts
That’s it for this week’s edition of Project Biohacking.
Whether it’s mainstream conversations like Joe Rogan’s on peptides or real-world results like my dog’s recovery, the goal is always the same: to give you actionable insights you can apply to your health journey.
If you found value in today’s issue:
Reply to the poll and let me know what you thought
Forward it to a friend who’s curious about peptides
Explore 1:1 coaching or personalized protocols here → Coaching
Until next time,
– Jeff
Founder, Project Biohacking
https://www.projectbiohacking.com/
How would you rate the content in this week’s issue?We’re constantly optimizing Project Biohacking — just like you optimize your health. Tell us how you’re liking the newsletter so far 👇 Your feedback helps shape future topics, improve structure, and make this more valuable for you. |
Disclaimer: I’m here to share what I’ve learned, not to replace your doctor. Always check with a qualified healthcare provider before trying anything new. And yes, peptides are often for research use only; please don’t turn your kitchen into a chemistry lab without supervision.